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keonigandall.com

Personal blog · keonigandall.com/posts · on HN as koengsciencephilosophy

keonigandall.com is a personal blog at keonigandall.com about science and philosophy. Since 2022, 3 different Hacker News readers have linked it 6 times. No feed was found, so read it on the site itself.

No feed foundVisit the blog
6mentions?
3HN people?
2022–2025first – last linked?
Links on Hacker News per year · peak 3 in 2024

Too few sampled comments (2) to say how often HN recommends it.?

Why HN links it

Keoni Gandall's blog, linked for a post on how to make DNA synthesis affordable and a post on whether scientific knowledge, especially in wet labs, can be passed on through papers alone.

Summarised by Claude from a sample of 2 HN comments that link here. Each comment is marked recommending, critical or neutral (citing without judging); how this works.

The author on HN?

koeng · 1,843 karma · member since 2019

It'd be pretty cool to build a cell, wouldn't it? keonigandall.com synbio25.com koeng101 X gmail.com github.com/koeng101/dnadesign

From their public HN profile, which links to this site.

What Hacker News says?

  1. Definitely! If you're willing to help, throw me an email so we can talk where it would best fit for you :) some sets of problems I have right now (on the hardware / software side): Hardware: It'd be great to have an open source plate gripper. I wrote a little bit about the general problem of transferring here - https://keonigandall.com/posts/transfer_problem.html . I have a uarm lite6, but wanted to investigate buil…

    Comment linking /posts/transfer_problem.html

    on “Ask HN: What are you working on? (October 2024)”
  2. The oldest sequenced DNA is 1.6 million years old. In the right conditions, it lasts far longer than pretty much any storage method right now. Plus I also sometimes store things in Bacillus subtilis, which is very hardy https://keonigandall.com/posts/sporenet.html

    Comment linking /posts/sporenet.html

    on “Ask HN: What non-AI products are you working on?”
  3. Github here - https://github.com/koeng101/dnachips It is a bit dead when it comes to a git, since I am trying to get the first machine needed, which is a DNA synthesizer (asked about that here https://groups.google.com/g/diybio/c/V3OYVBxaH04 for example). The idea is that with a traditional DNA synthesizer I can have positive controls of the chemistry, and develop a chip that can fit inside the flow cell of the exis…

    Comment linking /

    on “Ask HN: What interesting problems are you working on?”
  4. For anyone interested, found following blog post on OP’s website, which is linked to from their HN profile: _____ How to make DNA synthesis affordable https://keonigandall.com/posts/affordable_dna_2.html

    Comment linking /posts/affordable_dna_2.html

    on “Ask HN: What interesting problems are you working on?”
  5. I got a tube of this probiotic. They asked me not to sequence it, but I'm a little suspicious of putting it in myself, so trust-but-verify (probably Nanoporing). I literally cannot see why sequencing it is a "dick move", so I think I'll be doing it anyway. I do not buy that it is dangerous. However, I haven't seen any statistics showing the frequency of mutacin-1140 or its efficiency. Back in 2015 when I was a teen…

    Comment linking /posts/colicins.html

    on “Reasons not to take Lumina's anticavity probiotic”
  6. owenpalmer · 2025-03-22Recommends
    > imagine a PhD student who was never allowed to talk to other people, attend conferences etc., and could only read papers and try things in lab. But they can read papers extremely fast. Would they be successful? A lot of scientific knowledge cannot be communicated through papers. This is especially true in wet labs, where there's no procedural standardization. Keoni Gandall wrote an excellent post on this topic as…

    Comment linking /posts/too_much_tacit.html

    on “The Humans Building AI Scientists”

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